Tetragon Partners L.P. is an SEC-registered investment adviser based in New York, NY that reports managing 2 hedge funds on Form ADV. It reports $6.4 billion in regulatory assets under management. Its private funds, of all types, hold $4.4 billion in gross assets. Its disclosed U.S. stock holdings returned an estimated +26.5% 2025 YTD through Dec 31 (S&P 500: +16.4%), based on 13F filings. Over a longer period they returned an estimated +40.8% from Q3 2024 to Q4 2025, compared with +25.3% for the S&P 500, based on 13F filings.
- Regulatory assets under management
- $6.4 billionForm ADV Item 5.F
- Gross assets of private funds
- $4.4 billionAll private fund types, Form ADV
- Hedge funds managed
- 226 private funds in total
- Employees
- 122Form ADV Item 5.A
- Registration
- SEC-registered adviserCRD 156040
- Latest Form ADV
- 06/04/2026Disciplinary disclosures: none reported
Estimated 13F portfolio performance
| Quarter | Est. 13F return | S&P 500 |
|---|---|---|
| Q4 2025 | +15.9% | +2.4% |
| Q3 2025 | +4.0% | +7.8% |
| Q2 2025 | +12.2% | +10.4% |
| Q1 2025 | -6.4% | -4.5% |
| Q4 2024 | +8.5% | +2.1% |
| Q3 2024 | +2.6% | +5.4% |
Estimate of the firm's disclosed long U.S. stock portfolio from its quarterly 13F filings, holding each quarter-end portfolio to the next quarter-end at prices implied by all 13F filers. It is a price return before dividends and fees, ignores shorts, options, bonds, cash and trading within the quarter, and is not the return of any fund. Disclosures
Largest disclosed holdings
- Uipath Inc$286.0 million
- Kolibri Global Energy Inc$27.3 million
- Lyft Inc CL A Com$19.4 million
- Autolus Therapeutics PLC$18.9 million
- Sprinklr Inc$17.1 million
- Workiva Inc$12.9 million
- Annexon Inc$10.2 million
- Praxis Precision Medicines I$6.8 million
- Celldex Therapeutics Inc New Com New$6.6 million
- Arrowhead Pharmaceuticals In$6.4 million
As of 2025-12-31, from 13F filing by Tetragon Partners GP Ltd.
From SEC filings. Firm data comes from the SEC's Form ADV data as of Oct 2, 2026; performance estimates come from Form 13F. HedgeMountain has not verified this information, and it is not an offer, solicitation or recommendation. Full disclosures